Ipamorelin 20 Mg

Active substance: Ipamorelin

Pack : 10 vials x 2 mg

What is Ipamorelin and What Does It Do?

Ipamorelin is a synthetic peptide that belongs to a class of drugs known as growth hormone secretagogues (GHSs). It works by mimicking the action of your body's natural Ghrelin (the hunger hormone), binding to the ghrelin receptors in the pituitary gland and hypothalamus. This binding stimulates the pulsatile release of your body's own growth hormone (GH).

What sets Ipamorelin apart from other GHSs (like GHRP-6) is its high selectivity. It has a strong effect on GH release with a much lower incidence of stimulating appetite or increasing levels of the stress hormone cortisol and prolactin, making it a popular choice for those seeking a "cleaner" side-effect profile.

Claimed Benefits in Bodybuilding and Performance

By elevating GH levels, Ipamorelin users aim to achieve several key benefits relevant to bodybuilding:

1. Fat Loss: Increased GH enhances lipolysis (the breakdown of fat), helping to create a leaner, more defined physique, particularly by targeting stubborn abdominal fat.

2. Lean Muscle Growth: GH works synergistically with IGF-1 to promote protein synthesis and encourage moderate, quality muscle gains that appear "dry" and not bloated.

3. Enhanced Recovery & Improved Sleep: GH is critical for tissue repair. Users report significantly faster recovery between workouts, reduced muscle soreness, and deeper, more restorative sleep, which further amplifies natural GH production.

4. Improved Skin, Hair, and Nail Quality: Elevated GH and IGF-1 levels stimulate collagen synthesis, which can lead to thicker skin, stronger hair and nails, and potentially improved joint integrity.

5. Minimal Hunger Pangs: Unlike GHRP-6, which causes intense hunger, Ipamorelin's effect on appetite is very mild, making it much easier to use during cutting phases.

How is it Used (Protocol)?

Ipamorelin is typically administered via subcutaneous (Sub-Q) injection. Its half-life is relatively short, so timing and frequency are important to mimic the body's natural pulsatile release.

A standard bodybuilding protocol involves:

• Dosage: The common effective dose ranges from 200 mcg to 300 mcg per injection.

• Frequency: Typically administered 1-3 times per day.

• Timing: The most critical injection times are:

  • Pre-Bedtime: This is the most important dose, as it amplifies the body's largest natural GH pulse during deep sleep.

  • Post-Workout: To aid with muscle repair and nutrient shuttling.

  • Upon Waking: To counteract the catabolic state of an overnight fast.

• Crucial Administration Note: Ipamorelin must be injected on a fasting stomach. To ensure maximum effectiveness, avoid eating for at least 1-2 hours before and 30-60 minutes after the injection. Carbohydrates and high blood sugar can blunt its GH-releasing effects.

Known Side Effects and Risks

While Ipamorelin has a favorable side-effect profile compared to other peptides, it is not without potential risks:

1. Desensitization (Tachyphylaxis): Chronic, long-term use can lead to the pituitary gland becoming less responsive. To prevent this, users often follow a protocol of "cycling" (e.g., 5 days on, 2 days off, or 3 months on, 1 month off).

2. Water Retention: Some users experience mild subcutaneous water retention, though this is typically less pronounced than with other GH-secreting agents.

3. Numbness or Tingling: Transient numbness or tingling at the injection site is common.

4. Headaches and Dizziness: Some users report these, especially when first starting the peptide.

5. Insulin Resistance: Like any agent that elevates GH, long-term, high-dose use can potentially lead to decreased insulin sensitivity.

6. Carpal Tunnel Syndrome Symptoms: In sensitive individuals, elevated GH levels can cause fluid retention that puts pressure on the median nerve, leading to tingling in the hands.