HMG 750 Iu

Active substance: HMG

Pack: 10 vials x 75 iu

What is HMG and What Does It Do?

HMG stands for Human Menopausal Gonadotropin. It is a purified extract from the urine of postmenopausal women, containing two key hormones essential for reproductive function:

1. Follicle-Stimulating Hormone (FSH): In females, it stimulates ovarian follicle growth; in males, it supports sperm production.

2. Luteinizing Hormone (LH): In females, it triggers ovulation; in males, it stimulates the Leydig cells in the testes to produce testosterone.

In a medical context, HMG is used to treat infertility in both men and women. In the world of bodybuilding, it is used almost exclusively by males for one primary reason: to stimulate natural testosterone production, especially after a steroid cycle.

Claimed Benefits in Bodybuilding

The use of HMG in bodybuilding is highly specialized and is not for beginners or for casual muscle growth. Its purported benefits are specific:

1. Post-Cycle Therapy (PCT): This is its most common application. After a cycle of anabolic-androgenic steroids (AAS) or prohormones, the body's natural testosterone production is shut down. HMG, by mimicking LH and FSH, directly stimulates the testes to restart testosterone and sperm production. It is often considered a more powerful PCT agent than traditional SERMs (like Clomid or Nolvadex) for this purpose.

2. Testicular Preservation During a Cycle: Some users employ low doses of HMG during a steroid cycle to prevent testicular atrophy (shrinkage). The idea is that by providing exogenous LH-like activity, the testes continue to receive a signal to function, making recovery post-cycle potentially easier and faster.

3. Fertility Restoration: For bodybuilders concerned about fertility suppression due to long-term AAS use, HMG can be used to help restore sperm count and quality.

How is it Used (Protocol)?

HMG is administered via intramuscular (IM) or subcutaneous (Sub-Q) injection. It is a fragile peptide that must be reconstituted with bacteriostatic water and stored refrigerated.

Protocols vary widely based on goal and individual response, but general guidelines are:

• For Post-Cycle Therapy (PCT):

  • Dosage: Typically 75 IU to 150 IU, administered every other day or 2-3 times per week.

  • Duration: Used for 3-6 weeks, often overlapping with or preceding a SERM protocol (e.g., Clomid).

• For "On-Cycle" Testicular Preservation:

  • Dosage: A lower dose of 25 IU to 75 IU, administered 2-3 times per week throughout the cycle.

Crucial Note: Dosing is highly individual. Using too much can desensitize the Leydig cells, while using too little may be ineffective. Medical supervision is strongly advised.

Known Side Effects and Risks

HMG is a potent hormonal drug, and its side effects can be significant:

1. Hormonal Imbalances: As a gonadotropin, it can disrupt the delicate feedback loop of the hypothalamic-pituitary-gonadal (HPG) axis if misused.

2. Testicular Pain and Over-Stimulation: High doses can cause testicular swelling, pain, and discomfort.

3. Gynecomastia: The rapid increase in testosterone production can lead to its aromatization into estrogen, potentially causing the development of breast tissue in men.

4. Acne and Oily Skin: Related to the rapid fluctuation in hormone levels.

5. Cardiovascular Strain: Can increase hematocrit (red blood cell count), posing a risk for thrombosis.

6. Desensitization: As mentioned, chronic or high-dose use can lead to Leydig cell desensitization, counteracting the very goal of its use.

7. High Cost: Pharmaceutical-grade HMG is extremely expensive.