Femara Letrozole 2.5 mg 30 Tablets Nov.

What is Femara Letrozole 2.5 mg 30 tabs Nov.?

What is FEMARA and what is it used for?

FEMARA tablets are dark yellow colored, round, slightly curved, with sloped edges, "FV" on one side, and "CG" printed film-coated tablets. Each film-coated tablet contains 2.5 mg letrozole.

FEMARA is presented in blister packages containing 30 film-coated tablets.

Letrozole is a group of drugs called aromatase inhibitors. Treatment with FEMARA is a hormonal (or "endocrine") treatment of breast cancer.

The development of breast cancer is often stimulated by estrogens, the female sex hormones. FEMARA reduces the amount of estrogen by blocking an enzyme ("aromatase") that is involved in the production of estrogen, and thus can prevent the growth of breast cancers in need of estrogen to grow.

As a result, the tumor cells slow down or cut the progression and / or spread to other parts of the body. In addition, FEMARA can be used to reduce tumor size before breast surgery and to help prevent tumor recurrence after breast surgery.

Monitoring of FEMARA treatment

FEMARA should only be taken under strict medical supervision.

Your doctor will regularly check your condition to check whether the treatment has the desired effect.

Your doctor may also decide to monitor your bone health, as this medication can cause thinning or damage to the bones (osteoporosis, bone resorption).

Ask your doctor if you have any questions about how FEMARA is effective or why this medicine is prescribed to you.

How to use FEMARA?
Instructions for proper use and dose / frequency of administration

• The usual dose of FEMARA is 1 tablet once a day.

• Taking FEMARA at the same time every day will help you remember when to take your medicine.

• Always use FEMARA as instructed by your doctor. If you are not sure how to use it, consult your doctor or pharmacist.

• As long as your doctor specifies, continue to use FEMARA. You may need to use FEMARA for months or years.

• If you have any questions about how long you will continue to use FEMARA, talk to your doctor.

Application path and method

• FEMARA is for oral use only.

• Take the tablet  on a full stomach.

• Always swallow tablets with a glass of water at the same time every day.

• Do not chew, split or crush the tablet.

Use in children

FEMARA is not used in children or adolescents (under 18 years).

Use in the elderly

There is no specific dose recommendation for patients 65 years or older.

Special use cases

Dose adjustment is not necessary for patients with mild hepatic impairment or renal failure. However, patients with severe hepatic impairment should be kept under close supervision.

Unless your doctor recommends otherwise follow these instructions. Do not forget to take your medication in time.

Your doctor will tell you how long your treatment will take with FEMARA. Do not cut the treatment early because you cannot get the desired result.

Talk to your doctor or pharmacist if you have an impression that FEMARA's effect is too strong or too weak.

If you use more FEMARA than you should use

Talk to a doctor or pharmacist if you have used more than you should use from FEMARA.

You may need medical treatment. Take the tablet box with you and show it to your doctor.

If you have forgotten to use FEMARA

If you forget to take your medicine, take this dose as soon as you realize you forgot and take the next dose at the usual time.

If you remember that you forgot to take your medication at the very next hour (eg 2 or 3 hours) of the next dose (for example, 2 or 3 hours), give up the missed dose and take the next dose at the usual time.

Do not take double doses to compensate for forgotten doses.

The effects that may occur when terminating treatment with FEMARA

Termination of FEMERA treatment may cause your illness to worsen. Unless specified by your doctor, do not stop using FEMARA. If you have any questions regarding the use of FEMARA, consult your doctor or pharmacist.

What are the possible side effects?

As with all drugs, there may be side effects in people who are susceptible to substances present in the content of FEMARA.

The following side effects may occur as a result of using FEMARA:

If you have any of the following, stop using FEMARA and IMMEDIATELY tell your doctor or contact your nearest hospital emergency department:

• arm or leg (extremities) or percent weakness or stroke (paralysis), speech difficulties (stroke symptoms),

• chest pain or sudden arm or leg pain (symptoms of heart disease such as heart attack),

• Swelling and redness in a vein that is extremely sensitive and painful when touched [signs of blood clot formation (thrombophlebitis) due to inflammation of veins],

Difficulty in breathing, chest pain, fainting, rapid heartbeat, bluish discoloration of the skin [signs of blood clot formation such as obstruction of the blood vessels in the lungs (pulmonary embolism)],

• swelling of the arms, hands, feet, wrists or other parts of the body (signs of edema),

Mostly bloating in the face and throat [signs of allergic reaction],

• Severe fever, chills or mouth ulcers (mouth sores) caused by infection (inflammation-forming microbial disease) [symptoms of low white blood cells],

• Blurred vision (cataract symptoms),

• Yellowing of the skin and eyes, nausea, loss of appetite, dark urine (signs of jaundice),

• Rash, redness of the skin, swelling of the lips, eyes or mouth by collecting water, skin peeling, fever (signs of skin disease).

These side effects are very infrequent (up to 1 in 10,000 patients), infrequent (seen in 1 to 10 of 10,000 patients) and uncommon (seen in 1 to 10 of 1,000 patients) side effects.

These are all very serious side effects.

If you have one of these, you may need emergency medical care or hospitalization.

If you notice any of the following, tell your doctor immediately or contact the emergency department of the hospital nearest you:

• Pain in bones and joints,

• Hot flashes.

These side effects are very common (at least 10 out of 100 patients).

• bone thinning or damage (osteoporosis), which in some cases may lead to bone fractures,

• High cholesterol level (hypercholesterolemia).

These side effects are common (1 to 10 out of 100 patients).

• Impaired physical sensitivity (numbness),

• Palpitations, rapid heartbeat, elevated blood pressure (hypertension),

• Abnormal liver function test results (blood test disorders),

• Hardness in joints (arthritis),

• Fever.
These side effects are common (1 to 10 of 1,000 patients) side effects. All these are serious side effects. Emergency medical intervention may be required.

Tell your doctor if you notice any of the following:

• Headache,

• Dizziness,

• Feel bad in general,

• gastrointestinal diseases such as nausea, vomiting, indigestion, constipation, diarrhea,

• Increase in sweating,

• Pain in the muscles,

• Increase in body weight,

• Hair loss,

• Fatigue,

• Increase or loss of appetite,

• Depression.

These side effects are common (1 to 10 out of 100 patients).

• Urinary (urinary) system infection, frequent urination,

• vaginal diseases such as bleeding, discharge or dryness,

• Dry skin, itchy rash (urticaria),

• nervous system disorders such as anxiety, , irritability, hypersensitivity to stimuli, dizziness, memory problems, insomnia,

• pain or burning sensation in the hands or wrist (carpal tunnel syndrome),

• Eye irritation,

• Abdominal pain,

• Thirst, taste disturbance, dryness in the mouth,

• Cough,

• Reduced body weight,

• Dryness of mucous membranes,

• Breast pain.

These side effects are common (1 to 10 of 1,000 patients) side effects.

• Trigger finger; a medical condition where your finger or thumb is in the twisted position.

The frequency of this side effect is an unknown side effect. These side effects are the mild side effects of FEMARA.
Things to consider before using FEMARA
DO NOT USE FEMARA in the following cases:

If:

• If you are hypersensitive (allergic) to the excipients contained in Letrozole or FEMARA (consult your doctor if you think you may be allergic),

• If you still have menstruation (if you have not yet entered menopause),

• If you are pregnant,

• If you are breastfeeding.

USE FEMARA CAREFULLY

If:

• If you have a severe kidney disease,

• You have a severe liver disease.

• Your doctor may also decide to monitor your bone health, as this may lead to bone mineral loss and damage to it (osteoporosis).

Please consult with your doctor if these warnings are valid for you, even in any past period.

Food and beverage use of FEMARA

FEMARA can be taken with or without food.

Pregnancy

Consult your doctor or pharmacist before using this medication.

Do not use FEMARA if you are pregnant, as this may damage your unborn baby. Since FEMARA is only recommended for women in postmenopausal period, the restrictions on pregnancy will probably not apply to you. However, if you have recently become postmenopausal or are in the premenopausal state, you should talk to your doctor about the need to apply contraception, as you may have the potential to become pregnant.

If you find yourself pregnant during your treatment, consult your doctor or pharmacist immediately.

Breast-feeding

Consult your doctor or pharmacist before using this medication.

Do not breastfeed your baby if you use FEMARA. Tell your doctor if you are breastfeeding.

Vehicle and machine use

If you experience dizziness or or are experiencing impaired vision, do not use tools or machinery until you feel normal again.

Important information about some excipients in the content of FEMARA

FEMARA film coated tablets contain a substance called milk sugar (lactose). If you have been told by your doctor that you are sensitive to certain sugars, contact your doctor before taking this medicinal product.

Use with other drugs

Please inform your doctor or pharmacist if you are currently using any prescription or non-prescription medication, or if you have recently used it.

Warning!

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