What is Humatrope 72 iu 24 mg Lilly?
What is HUMATROPE and what is it used for?
The cartridge containing powder for the HUMATROPE injection solution contains 24 mg of somatropin called human growth hormone. The powder is white or close to white. The solvent syringe contains a clear solution.
Human growth hormone is a hormone in the protein structure and is produced by a special process called the recombinant DNA technology process in the laboratory. It is in the same structure as the hormone produced in our body.
The growth hormone regulates the growth and development of cells in your body. It stimulates the growth of the cells in the long bones of the spinal cord and legs and provides heightening.
In growth hormone deficiency, growth hormone increases bone mineral content, muscle cell size and number, and reduces body fat stores.
• Used in the treatment of the following disorders in children and adolescents:
- Insufficient production of growth hormone (Growth hormone deficiency).
- The absence of some or all of the x-sex chromosomes in girls with short stature (Turner syndrome)
- Kidney failure in adolescents with growth retardation (chronic renal failure)
- young children at age 4 or older not in the normal size (SGA = small by gestational age)
• It is used in the treatment of adults with growth hormone deficiency at the beginning of childhood or adulthood.
How to use HUMATROPE
Instructions for proper use and dose / frequency of usage
If your doctor has told you how to take HUMATROPE, always take it that way. If you are not sure how to use HUMATROPE, consult your doctor or pharmacist.
Generally treatment with HUMATROPE is a long-term treatment; Your doctor will adjust your dose over time based on your body weight and response to treatment. In general, the dose was calculated according to the following recommendations and as a single dose per day.
In children and adolescents:
• Growth hormone deficiency
0.025-0.035 mg per kg per day
• Turner syndrome
0.045-0.050 mg per kg per day
• Chronic renal failure
0.045-0.050 mg per kg per day
• Gestational births
0.035 mg per kg per day. If the child does not respond to treatment or has reached the final height and stopped growing, treatment should be discontinued after the first year.
Growth hormone deficiency in adults:
Treatment should be started at 0.15-0.30 mg daily with a low initial dose. Lower initial doses may be required for elderly and overweight patients. Initial doses can be increased gradually according to your individual requirements. The total daily dose usually does not exceed 1 mg.
The dose requirement may be decreased depending on the increasing age. Women receiving oral estrogen replacement therapy may need higher doses than men.
Use in the elderly
Elderly patients are more sensitive to the effects of HUMATROPE and may be more prone to side effects.
Special use cases
No studies were conducted with HUMATROPE.
Unless your doctor recommends otherwise follow these instructions. Do not forget to take your medication in time.
If you have an impression that the effect of HUMATROPE is too strong or too weak, talk to your doctor or pharmacist.
If you have used more HUMATROPE than you should:
Talk to a doctor or pharmacist.
• If you have injected too much HUMATROPE, your blood sugar may be reduced to very low (hypoglycemia) levels at the beginning and then it may reach very high (hyperglycemia) levels.
• If you inject too much HUMATROPE over a long period of time, your body may have overgrowth in some areas, such as the ear, nose, chin, hands and feet (acromegaly).
If you forgot to use HUMATROPE
Your doctor will decide when the missed dose will be used.
It is important to follow your doctor's instructions for the new usage time of the following dose. Do not take double doses to compensate for forgotten doses.
Effects after termination of treatment with HUMATROPE
You should use HUMATROPE as your doctor told you. Your doctor will tell you how long your treatment will take with HUMATROPE. Do not cut the treatment early because you cannot get the desired result. You should not stop using HUMATROPE without telling your doctor.
Side effects :
Very Common Side Effects:
Arthritis pain (arthralgia)
Common side effects:
Pain in the injection site.
High blood sugar (hyperglycemia)
Hypersensitivity to metachrezol or glycerol.
Low thyroid hormone levels
Sleep disorders (insomnia)
Tingling and numbness of palms and fingers due to nerve compression in the wrist (carpal tunnel syndrome)
Localized muscle pain (myalgia)
High blood pressure (hypertension)
Shortness of breath (dyspnea)
Temporary sleep in sleep (sleep apnea)
Uncommon Side Effects:
Breast growth (gynecomastia)
Rare Side Effects:
- Severe and frequent headache accompanied by nausea and vision problems with increased intracranial pressure (increased intracranial pressure caused by benign tumors). If this is seen, tell your doctor immediately.
- Sugar in glucose (glucosuria)
Leukemia has been reported in a small number of children treated with growth hormone. However, there is no evidence of increased leukemia in patients receiving growth hormone.
Inform your doctor or pharmacist if any of these side effects become more severe or if you experience any side effects not mentioned in these instructions.
Storage of HUMATROPE
Keep HUMATROPE out of the reach of children and in its packaging.
Before preparation: Store HUMATROPE cartridges and solvent in the refrigerator at 2-8oC. Do not freeze.
After preparation: HUMATROPE cartridges can be stored for 2 days at 2-8oC in the refrigerator after reconstitution. Diluted cartridges should not be left outside the refrigerator for more than 30 minutes at each use. Pens should not be stored with pins attached. Diluted HUMATROPE cartridges should not be frozen.
Reminder: This medicine is for you or your child, do not give to others. Even if the symptoms of their disease are the same as yours, the medication can harm them.
Do not use HUMATROPE after the expiration date in the packaging.
Do not use the HUMATROPE if you notice turbidity in the product or if there are defects in the particle and / or its packaging.
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